19 results
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine • 1ml blood ... urine sediment Microscopic ... Diagnostic of GN or vasculitis ... microscopic and ... #renal #urine #blood
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Alloimmune • anti-HLA antibodies ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Algorithm Normal Blood ... B12 - Anti-IF Antibodies ... Myelodysplastic Syndromes ... #Hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... • Sjögren syndrome ... ANCA-Associated Vasculitis ... : • Microscopic ... #diagnosis #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... Microscopic polyangiitis ... diagnosis #table #rheumatology ... #antibodies
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Water - Pus - Blood ... Pulmonary HTN - Vasculitis ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... : - Anemia
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... #diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... tract, and often causes ... Dx: GPA, EGPA, microscopic ... C-ANCA) pattern: antibodies ... differential #diagnosis #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Infection - Vasculitis ... Sjogren's, GPA, EGPA, Microscopic ... : • Complete blood ... • Fecal occult blood
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Investigations: full blood ... dipstick, urine microscopy ... osmolarity If cause ... Glomerulonephritis / Vasculits ... screen, including blood