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diagnosis differential antibodies classification algorithm ana antinuclear dermatology diseases workup acute aki antibody antineutrophil arthritis associations autoantibodies bloodsmear borrelia causes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
cases • Sjögren syndrome ... Vasculitis: • ... Microscopic polyangiitis ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
): • Microscopic ... pulses, bruis, or blood ... Large Vessel: Blood ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- Vasculitis, e.g ... granulomatosis p-ANCA ... - Vasculitis, e.g ... Microscopic polyangiitis ... diagnosis #table #rheumatology
ANCA-Associated Vasculitis There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... Vasculitis There ... pathologically or clinically ... inflammation: • Microscopic ... diagnosis #algorithm #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
small vessels - ANCA-associated ... granulomatosis - microscopic ... Churg-Strauss syndrome ... - Sjögren syndrome ... Vessels #Diagnosis #Rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vasculitis Involving ... • ANCA Associated ... : - Microscopic ... Disease • Cogan syndrome ... #dermatology #rheumatology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Investigations: full blood ... dipstick, urine microscopy ... investigations depending on clinical ... Glomerulonephritis / Vasculits ... : ANCA, ANA, Anti-GBM
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulses, bruits, or blood ... )): Microscopic ... • Behcet syndrome ... • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... : • Clinical triad ... DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... classification #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... vasculitis (AAV ... polyangiitis), MPA (microscopic ... reveals increasing blood ... FINDINGS: • U/A: microscopic
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