14 results
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
ANCA-Associated ... Includes granulomatosis ... polyangiitis (GPA), microscopic ... involvement - PR3>MPO Microscopic ... #Diagnosis #Rheumatology
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... eosinophils No granulomatous ... inflammation: • Microscopic ... StanfordChiefs #ANCA ... diagnosis #algorithm #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
cases • Sjögren syndrome ... Vasculitis: • Microscopic ... + 90% • Granulomatosis ... + 90% • Granulomatosis ... antibodies #diagnosis #rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Granulomatosis with ... Polyangiitis (GPA) and Microscopic ... Polyangiitis (MPA) - ANCA ... Polyangiitis #GPA #Microscopic ... Guidelines #algorithm #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Graves' disease c-ANCA ... Wegener's granulomatosis ... p-ANCA - Vasculitis ... Microscopic polyangiitis ... diagnosis #table #rheumatology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pauci-Immune: - ANCA-positive ... (Eosinophilic granulomatosis ... polyangiitis, Granulomatosis ... polyangiitis, Microscopic ... polyangiitis) - ANCA-negative
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
small vessels - ANCA-associated ... - Wegener granulomatosis ... - microscopic ... Churg-Strauss syndrome ... Vessels #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
): • Microscopic ... glomerulonephritis - Granulomatous ... VESSEL VASCULITIS (Granulomatous ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Manifestations of Granulomatosis ... involvement in granulomatosis ... Polyarteritis nodosa • Microscopic ... • Goodpasture syndrome ... rash #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Mucocutaneous lymph node syndrome ... )): Microscopic ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology