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diagnosis treatment aplastic leukemia acquired algorithm arteritis cancer cardiology cardiomyopathy chronic classification cll community comparison differential differentiation emergencies gca giantcell
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
- pulmonary opacities ... Diagnosis: >3 symptoms ... sepsis), PE, DAH, CHF ... #diagnosis #management ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... progress to MDS ... #diagnosis #management ... #treatment #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... manifestations, hypoxia, CXR ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Hypocellular/Hypoplastic MDS ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Diagnosis and Management ... , signs, and complications ... can include: ... or MDS ... Summary #treatment #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
ARDS to explain symptoms ... : Age>60, CKD, CHF ... fluid balance, and CXR ... with pulmonary ... Transfusion #Reactions #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... syndrome): - Hematologic ... - Occurs after CAR-T ... speech changes (CAR-T ... renal failure, pulmonary
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... progression to AML ... factors (examples: G-CSF ... Syndromes #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... ingestion • B symptoms ... classification #hematology ... #oncology #management
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