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diagnosis hematology algorithm differential management oncology workup myelodysplastic pancytopenia treatment acute aki causes gravis hematololgy injury kidney mcv myasthenia myelodysplasia
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... vs Hypocellular MDS ... Zhuoer Xie, MD ... @ZhuoerXie #Aplastic ... #Anemia #diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... • Symptomatic anemia ... Can progress to MDS ... Medicine @SCVMCMed #Aplastic
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach to Anemia ... Non-hemolytic: ACD, Aplastic ... anemia, CKD • ... Reticulocytosis, MDS ... Matthew Ho, MD
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome (MD ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... Myelodysplastic #Syndrome #MDS
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes (MDS ... platelets) • MDS ... precursors MDS ... • Aplastic Anemia ... chemotherapy #MDS
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
clinical context and signs ... Anti-GBM, Anti-ds-DNA ... cryoglobulins, hepatitis serology ... , HIV serology, ... Differential #Diagnosis #nephrology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
distribution in the 30s ... test - Cogan sign ... - Peek sign ... immunosuppressants - Meds ... diagnosis #management #neurology
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