10 results
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... group of disorders ... caused by blood ... • AnemiaAplastic ... Neutropenia • Platelet Disorders
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... • Hypocellular myelodysplastic ... syndrome (MDS)
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... #Syndrome #MDS
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Consumption Disorders ... HLH syndrome 5. ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Consumption Disorders ... HLH syndrome 5 ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Small Bowel Disorder ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... #Causes #Hematology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... osmolarity If cause ... clinical context and signs ... Anti-GBM, Anti-ds-DNA ... #causes
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Hematologic • Anemia ... Pulmonary Disease Neurologic ... • Somatization Disorder ... Chronic Fatigue Syndrome
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
• Symptoms and signs ... Non-compressive Spinal Cord Causes ... MCTD, Sjogren syndrome ... #diagnosis #neurology ... differential #algorithm
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... distribution in the 30s ... test - Cogan sign ... - Peek sign ... diagnosis #management #neurology