10 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... syndrome (MDS) ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... Syndrome (MD) - ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... #Syndrome #MDS
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... platelets) • MDS ... precursors MDS ... • Aplastic Anemia ... chemotherapy #MDS
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... • Symptomatic anemia ... Can progress to MDS ... Medicine @SCVMCMed #Aplastic
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Abnormalities: macrocytic anemia ... multiple myeloma, myelodysplastic ... syndrome (MDS) ... multiple myeloma or myelodysplastic ... syndrome (MDS)
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
HLH syndrome 5. ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... marrow failure syndrome
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
HLH syndrome 5 ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... marrow failure syndrome
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
clinical context and signs ... Anti-GBM, Anti-ds-DNA ... , HIV serology, ... Abdominal compartment syndrome ... • Cardio-renal syndrome
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
distribution in the 30s ... test - Cogan sign ... - Peek sign ... immunosuppressants - Meds ... diagnosis #management #neurology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Myelodysplastic ... syndromes current ... syndromes (MDS) ... Patients with MDS ... disease tolerate anemia