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diagnosis differential algorithm hematology cardiology celiac disease gastroenterology management nutrition pressure pulse symptoms erythematosus fe gca giantcell gravis lupus mds
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Pregnancy, EPO treatment ... Elite athletes • Chronic ... Loss (without anaemia ... ) #Iron #Deficiency
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... : Gl lesions / cancer ... Inflammation: IBD, Chronic ... #Deficiency #Causes ... differential #diagnosis #anemia
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... Increased hepcidin: Chronic ... Waldenstroms, Rheumatoid arthritis ... and other chronic ... #Diagnosis #Causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... RA, SLE, PRV, Chronic ... Inflammation • Cancer ... • Early Iron ... Deficiency #
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... : • Acute or Chronic ... effect following treatment ... malignancy • Iron ... deficiency anemia
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
suspected: • Signs ... celiac disease • Iron-deficiency ... anemia unresponsive ... to treatment ... without discernable cause
Causes of Wide Pulse Pressure - Differential Diagnosis Physiologic: • Advanced age-arteriosclerosis (less compliant arteries) • Well
Causes of Wide Pulse ... less compliant arteries ... hypovolemia - Severe iron ... deficiency anemia ... disorders - Chronic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... Marrow Failure • Chronic ... or folic acid deficiency ... • Copper deficiency ... rings of excess iron
Celiac Disease - Clinical Manifestations Gastrointestinal Manifestations: • Diarrhea, Loose stools, Dyspepsia, Flatulence, Chronic abdominal pain,
pain, Vomiting, Chronic ... , Hepatitis • Iron-deficiency ... anaemia • Arthralgia ... , Arthritis, Osteopenia ... Celiac #Disease #signs
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
Physiologic Causes ... less compliant arteries ... conditions) • Severe iron ... deficiency anemia ... disorders - Chronic
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