13 results
hematology diagnosis differential management oncology aplastic pancytopenia anemias cancer chronic cll essential et hemolytic leukemia lymphocytic macrocytic mcv myelodysplasia myelodysplastic
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypoproliferative Macrocytic Anemia ... Deficiency • MDS ... #Macrocytic #Anemia ... differential #diagnosis #algorithm ... #hematology #workup
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Signs of anemia ... • Extrinsic RBC ... • Intrinsic RBC ... Matthew Ho, MD ... #hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Spherocytosis, G6PD, PK, HbC ... Reticulocytosis, MDS ... #MCV #Algorithm ... Differential #Diagnosis #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Treatment: • Consider ... Can progress to MDS ... diagnosis #management #treatment ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... Differential Diagnosis Algorithm ... Acquired Aplastic Anemia ... • Hypoplastic MDS ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
myelodysplastic syndrome (MDS ... Hypocellular/Hypoplastic MDS ... abnormalities typical for MDS ... Pancytopenia: • ↓ RBC ... Treatment:
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Matthew Ho, MD
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
incidentally via CBC ... present, symptoms, signs ... transformation into AML or MDS ... • Treatment algorithms ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes (MDS ... formed or don’t work ... platelets) • MDS ... precursors MDS ... chemotherapy #MDS
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