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diagnosis differential endocrinology hypercalcemia algorithm hypocalcemia nephrology signs symptoms carcinoma cholecalciferol chondrocalcinosis ckd clinical cppd diaphyseal disease fracture hypomagnesemia management
Impact and Challenges With Vitamin D to Treat Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease
Treat Secondary Hyperparathyroidism ... Calcitriol ... or better than calcitriol ... or better than calcitriol ... VitaminD #Secondary #Hyperparathyroidism
Causes of Hypercalcemia Parathyroid gland structure-related • Primary hyperparathyroidism • Parathyroid adenoma • Parathyroid hyperplasia • Parathyroid
Causes of Hypercalcemia ... structure-related • Primary hyperparathyroidism ... prostate (release of calcitriol ... disease • Tertiary hyperparathyroidism ... Hypercalcemia #Causes
Workup of Hypercalcemia - Differential Diagnosis Algorithm High or Normal PTH: • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Normal PTH: • Hyperparathyroidism ... : Parathyroid adenoma ... , Parathyroid hyperplasia ... , Parathyroid carcinoma ... diseases, Idiopathic calcitriol
Hypomagnesemia (Serum level < 1.7 mg/dL) Neuromuscular manifestations • Tremor, tetany, seizures • Weakness
Hypocalcemia • Hypoparathyroidism ... • Parathyroid ... Decreased synthesis of calcitriol
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... Parathyroid hormone–dependent ... Primary hyperparathyroidism ... Neoplasms - Parathyroid ... Hypercalcemia #Causes
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 Hypocalcemia - Differential Diagnosis Algorithm • Low Serum Mg: GI losses, Renal losses, Alcoholism, Malnutrition, Drug-Induced
Elevated - Secondary Hyperparathyroidism ... Inappropriately Normal/Low - Hypoparathyroidism ... Destruction of parathyroid ... sunlight • Other Causes ... Diagnosis #Algorithm #causes
Radial Fracture Due to Parathyroid Carcinoma- ...A plain radiograph of the left arm showed a diaphyseal
Fracture Due to Parathyroid ... diagnosis of primary hyperparathyroidism ... which is a rare cause ... of primary hyperparathyroidism ... radial #fracture #hyperparathyroidism
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
normal): • Primary Hyperparathyroidism ... PTH: • Elevated Calcitriol ... Diagnosis #Algorithm #causes
Causes of Hypocalcemia by Clinical Cause Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from
Causes of Hypocalcemia ... by Clinical Cause ... illness - Secondary hyperparathyroidism ... disease - Secondary hyperparathyroidism ... #Hypocalcemia #Causes
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 Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
vast majority of cases ... production - Hyperparathyroidism ... Incr levels of parathyroid
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