25 results
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... Heart failure - CAD ... Tamponade Pulmonary Causes ... syndrome Other Causes ... Transverse myelitis • Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... Splenomegaly - CTD ... EGPA - MPA • CTD ... Differential #Diagnosis #hematology ... #rheumatology #
Diabetes – diabetic nephropathy
Majority of the literature in the area is applied to the diabetic nephropathy
be the primary cause ... - Cytokines #Pathophysiology ... #Nephrology #CKD
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
NSAIDs cause vasoconstriction ... use shouldn't cause ... patients have CKD ... Nephrology #Renal #Pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... factors: Age>60, CKD ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
• IgG type ± C3d ... 2) LOOK FOR a cause ... management #treatment #rheumatology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Normal CK ... Weakness, Incr CK ... Myopathy (Also caused ... therapy), Normal CK ... Complications #pathophysiology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... diagnosis #algorithm #rheumatology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... Physiologic Causes ... Pathologic Causes ... Worse outcomes in CKD ... Differential #Diagnosis #Pathophysiology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
considered in all cases ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential