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diagnosis hematology differential causes oncology management cll lymphocytic thrombocytosis ckd common cvid erythematosus hemeonc hemodialysis hypogammaglobulinemia immunodeficiency immunology increased lupus
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelogenous Leukemia ... : • Acute or Chronic ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... #Causes #Hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Differential Diagnosis Algorithm ... • Epinephrine Cancer ... Myeloproliferative Disorder • Chronic ... myelogenous leukemia ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Differential Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Inflammation • Cancer ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... - infiltrates (anemia ... , thrombocytopenia ... lymphoid organs When Cancer ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... 5) Symptoms of anemia ... or thrombocytopenia ... or thrombocytopenia ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Cancer affecting ... • Neutropenia, anemia ... , thrombocytopenia ... #CLL #Chronic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... hemolysis, deficiency anemia ... Malignancy: Metastatic cancer ... Inflammatory Conditions: Rheumatologic ... • Infections: Chronic
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Autoimmunity • Chronic ... Lymphoma or other cancers ... gastric and breast cancer ... specifically immune thrombocytopenia ... autoimmune hemolytic anemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia ... IDUS) • Immune Thrombocytopenia
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