10 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Inflammatory: • IBD ... disease Tissue Damage ... effect following treatment ... #Hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... signs of end organ damage ... • Treatment: ... Syndrome #TLS #diagnosis ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Fibrinolysis → End organ damage ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
A quick infographic on the importance of sun protection and the various results of sun damage
#sun #damage #UV ... #wavelengths #causes ... #diagnosis #dermatology ... Welsh MM, Karagas MR ... Mechanisms and treatments
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Mechanisms: • Direct Damage ... and petechiae Causes ... aplastic anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... - MRI: inflammation ... and lower jaw Treatment ... #diagnosis #management ... #Dermatology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... MI, stroke, DVT/ ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome caused ... or triggers) is crucial ... • Tissue damage ... #Management #Hematology
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
tissues, leading to damage ... X-rays, CT, or MRI ... TREATMENT OPTIONS ... Smoking cessation is crucial ... #Management
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
Muscle atrophy may cause ... was diagnosed in ... positive patients Treatment ... #management #rheumatology ... #dermatology