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diagnosis clinical differential ophthalmology video physicalexam ocular slitlamp pathophysiology algorithm hematology management nephrology pathology rheumatology radiology signs causes classification symptoms
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
A (AA) → Chronic ... nephropathy is common in AA ... (AMYLOID ANGIOPATHY ... light chain AA ... IL-1 & IL-6 → AA
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Features: POEMS, AL amyloid ... • Organized Ig deposits ... : Ig-related amyloid ... Non-organized Ig deposits ... monoclonal Ig deposits
Nephrotic Syndrome - Classification - Podocytopathies - Immunocomplex Deposits - Other substances Deposits #Nephrotic #Syndrome
Immunocomplex Deposits ... Other substances Deposits
Great Mimickers - SHALLOTS Mnemonic S- Syphilis - Neurosyphilis, aortitis, gummas... Granulomas can form anywhere! Skin, mucosa,
A - Amyloid - Amyloid ... deposits everywhere
This image shows spicular amyloid deposits showing blunt conical formations with interconnecting fibrils. Dr. Stephen Bonsib via
shows spicular amyloid ... deposits showing ... arkanalabs #amyloid ... #deposits #deposition
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 Amyloidosis Types - Comparison Table Proteins depositing where they shouldn't • AL • TTR • AA Julia Gips,
AL • TTR • AA
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Pathophysiology • DDx: AA
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
glomerulopathy (Dense deposit ... Minimal immune deposits
This image shows portions of glomerular tuft with collapsed GBM (across top), spicular amyloid (middle right),
top), spicular amyloid ... ), and nodular amyloid ... glomerulus #GBM #amyloid ... #desposition #deposits
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 Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Extravascular lg Deposits ... Intravascular lg deposits
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