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diagnosis differential dermatology lupus sle systemic symptoms myopathy myositis skin vasculitis antimda5 antimda5dm antinxp2 antinxp2dm arthritis autoantibodies autoimmune classification comparison
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Seborrhea • Dermatomyositis ... • Rheumatic fever ... Vesicopustule on erythematous ... Discoid lupus erythematosus ... differential #diagnosis #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... chest (in a V-sign ... violaceous macules and erythematous ... • Fever: up to ... #rheumatology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Malar rash 40% - Fever ... Systemic #Lupus #Erythematosus ... autoantibodies #signs ... #differential #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... Still disease, dermatomyositis ... Non-autoimmune rheumatologic ... to: Arthritis, Fever ... #Diagnosis #Rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Anti-Jo, +Anti-Mi2 Dermatomyositis ... proximal joints, Fever ... pain and/or joint aches ... diagnosis #comparison #rheumatology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
butterfly-like erythematous ... lighter center and erythematous ... not be seen try focus ... Suggestive of: Rheum Fever ... migrans: • Target sign
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... SLE) - Typical Signs ... Symptoms Alopecia, Fever ... #SLE #Signs #Symptoms ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Coronary arteries - Fever ... systemic lupus erythematosus ... Vasculitis: • Fevers ... purpura: strong sign ... differential #diagnosis #rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
with edema • Erythematous ... chest (in a V-sign ... shoulders (in a shawl sign ... violaceous macules and erythematous ... diagnosis #management #rheumatology
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