18 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
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Systemic Lupus Erythematosus ... Malar rash 40% - Fever ... Systemic #Lupus #Erythematosus ... autoantibodies #signs ... #differential #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
SKIN RASHES 



Skin rashes can occur from a variety of factors, including infections, heat, allergens, immune
important to make treatment ... petechial/purpuric, erythematous ... the presence of fever ... and systemic signs
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... megaloblastic anemia Treatment ... if neutropenic fever ... diagnosis #management #treatment ... #hematology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
butterfly-like erythematous ... lighter center and erythematous ... not be seen try focus ... Suggestive of: Rheum Fever ... migrans: • Target sign
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... SLE) - Typical Signs ... Symptoms Alopecia, Fever ... #SLE #Signs #Symptoms ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Systemic lupus erythematosus ... - Nonremitting fever ... systemic lupus erythematosus ... Treatment: • Corticosteroids ... #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
with edema • Erythematous ... chest (in a V-sign ... violaceous macules and erythematous ... Dermatomyositis • Fever ... Dermatomyositis #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis: HLH signs ... following: • Fever ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology