20 results
Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Aplastic Anemia ... vs Hypocellular MDS ... Expectation • Rx Algorithm ... #Anemia #diagnosis ... #oncology #hematololgy
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... hypocellular bone marrow biopsy ... Can progress to MDS ... #Anemia #diagnosis ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
, Bone marrow Biopsy ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
, Bone marrow Biopsy ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... MDS • Congenital ... #Algorithm #Hematology
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
Deficiency • MDS ... #Macrocytic #Anemia ... #differential #diagnosis ... #algorithm #hematology ... #workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach ... Diagnosis Framework ... Non-hemolytic: ACD, Aplastic ... Reticulocytosis, MDS ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... • Bone marrow biopsy ... only curative treatment ... #treatment #hematology
Initial triage of the neutropenic adult - Algorithm for the evaluation and treatment of adult patients
neutropenic adult - Algorithm ... evaluation and treatment ... #neutropenia #Algorithm ... #workup #diagnosis ... #hematology #biopsy
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Hypocellular/Hypoplastic MDS ... anemia Treatment ... #hematology #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Matthew Ho, MD ... #Algorithm #hematology