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differential oncology management pancytopenia mds neutropenia cancer causes cell chronic classification cll disorders eosinophil eosinophilia hodgkins indications leukemia lymphocytic lymphoma
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
- Differential Diagnosis ... Algorithm Sequestration ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... #Algorithm #Causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... • Bone marrow biopsy ... #hematology #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... hypocellular bone marrow biopsy ... Treatment: • Consider ... #Anemia #diagnosis ... #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... , Bone marrow Biopsy ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Pancytopenia - Workup ... , Bone marrow Biopsy ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Algorithm #Hematology
Initial triage of the neutropenic adult - Algorithm for the evaluation and treatment of adult patients
neutropenic adult - Algorithm ... evaluation and treatment ... #neutropenia #Algorithm ... #workup #diagnosis ... #hematology #biopsy
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... • Hypocellular myelodysplastic ... anemia Treatment ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... Workup: • Complete ... #Syndromes #diagnosis ... #hematology #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... hemolysis, deficiency anemia ... Rebound effect from treatment ... #Algorithm #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... glucocorticoid treatment ... consider tissue biopsy ... #Differential #diagnosis ... #hematology #eosinophilia
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