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differential causes management oncology thrombocytosis approach ckd classification elevatedmcv hemodialysis iron macrocytosis mcv microcytic myelodysplasia myelodysplastic nephrology normocytic platelets pruritus
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Algorithm Blood ... MCHC, Serum Iron, Ferritin ... • Aplastic Anemia ... • Anemia of Chronic ... #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Diagnosis Framework ... Non-hemolytic: ACD, Aplastic ... Reticulocytosis, MDS ... #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Diagnosis Algorithm ... Labs: Ferritin ... Matthew Ho, MD ... #Diagnosis #Algorithm ... #ferritin #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... effect following treatment ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
- Differential Diagnosis ... Algorithm Decreased ... (Eg Causes: Chronic ... #Algorithm #Causes ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Algorithm Decreased ... • Marrow Aplasia ... RA, SLE, PRV, Chronic ... • Early Iron Deficiency ... #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... , GATA2 deficiency ... anemia Treatment ... #hematology #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Acute hemolysis, deficiency ... anemia, Rebound ... effect from treatment ... • Infections: Chronic ... #Algorithm #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... Marrow Failure • Chronic ... • Copper deficiency ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Management of Pruritus in Patients with Chronic Kidney Disease Pruritus with no primary lesions - differential diagnosis:
Patients with Chronic ... - differential diagnosis ... pruritus • Hematologic ... pruritus (Iron deficiency ... #Pruritus #Treatment
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