45 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... maculopapular rash ... synovitis (40%) Treatment ... #AOSD #rheumatology ... #treatment
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Joint Pain Rash ... infection Malar rash ... infection • Lyme disease ... #differential #diagnosis ... #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... Differential Diaqnoses ... #diagnosis #management ... #treatment #rheumatology
Algorithm for Diagnosis of the Vesiculobullous Rash

Febrile, Diffuse Distribution:
 - Varicella,  Smallpox,  Disseminated, Gonococcal,
Algorithm for Diagnosis ... Vesiculobullous Rash ... Hand Foot & Mouth Disease ... #Algorithm #Diagnosis ... #Dermatology #Skin
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Algorithm Spurious ... disorders • Celiac disease ... effect following treatment ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... #Algorithm #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... Differential Diagnosis ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
maculopapular skin ... Treatment - Mild ... : NSAIDS Treatment ... #AOSD #diagnosis ... #rheumatology #
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... bruising • Skin ... factor VIII) Treatment ... VonWillebrand #Disease ... #Diagnosis #Hematology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
redness of the skin ... includes Kawasaki disease ... erythematous rash ... #Diagnosis #Dermatology ... #Erythematous #Rash