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diagnosis differential gastroenterology lfts transaminitis aclf acute aih alcoholic autoimmune chemistry chronic cirrhosis criticalcare drug druginduced hepatocellular idiosyncratic induced interpretation
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
disease, liver ... Injury (DILI) ... Viral Hepatitis ... Procedures Management ... #Hepatology #gastroenterology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... disease 6-9 mo ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Stepwise Diagnosis Algorithm ... disease, Hepatic ... #Liver #Injury ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... • Iatrogenic: DILI ... #injury #hepatitis ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury → liver ... failure 1) Hepatocellular ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Failure (ALF): ... • Liver injury ... of cholestatic disease ... disease: > 2 ... #differential #Hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... to acute liver ... failure ... injury, though ... #Hepatology
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Insufficiency, Liver ... Failure, Toxins ... , Severe Valve Disease ... • Obstructive: Pulmonary ... #treatment #management
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
- Management Algorithm ... - Acute kidney injury ... HCV, DILI, HCC, ... #Management #Algorithm ... #hepatology
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