373 results
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
, Hypokalemia, Erectile ... higher risk of hyperkalemia ... (ACEI, ARB, diabetes ... ) ACE inhibitors ... - Pregnancy, Hyperkalemia
ACEI or ARB Initiation
Hyperkalemia:
 - Review concurrent drugs
 - Moderate potassium Intake
 - Consider: diuretics, sodium
ACEI or ARB Initiation ... Hyperkalemia: ... artery stenosis #ACEI
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Angiotensin-converting enzyme (ACE ... MunerMohamed1 #hyperkalemia
The Diagnostic Approach to Hyperkalemia
Drugs
 - Amiloride
 - Spironolactone
 - Triamterene
 - Trimethoprim
 - Pentamidine
 -
Diagnostic Approach to Hyperkalemia ... LMW heparin - ACE-I ... Beta-Blockers #Hyperkalemia
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... happypillsrx/ #Hyperkalemia
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... • NSAIDs • ACE ... cantaloupe #hyperkalemia
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Aldosterone • ACEi ... • NSAlDs #Hyperkalemia
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Hypokalemia ... Hyperkalemia ... Drug-induced hyperkalemia ... ACE-Is and ARBs
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Suspicion for Hyperkalemia ... Drugs Causing Hyperkalemia ... • NSAIDs • ACE ... images/12834 #hyperkalemia
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
: Treatment of Hyperkalemia ... who have chronic hyperkalemia ... ACE inhibitors, ... carry the risk of hyperkalemia ... Binder #KBinder #Hyperkalemia