19 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
) Clinical Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... prevention (statin for CVA ... #CNS #neurology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
lupus cases, drug-dependent ... to 1:1 F:M • Clinical ... • Immunologic Workup ... • Immunologic Workup ... Evolution: Chronic disease
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... • Immunologic Workup ... Positive in 60-80% of cases ... Evolution: Chronic disease ... Management #Summary #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... test, ANA (e.g., SLE ... (CVID, WAS), (neurologic ... not required in all ... #Workup #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... erythematosus (ACLE ... lymphoproliferative syndrome Clinical ... and CNS • Headache
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... of Membranous Lupus ... for worsening disease ... therapy (MMF plus CNI ... Treatment #management #nephrology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
RED FLAGS - In all ... cases there are ... suspicion of severe disease ... splenomegaly, abnormal neurology ... #Limping #NWB #Algorithm
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... approach to kidney disease ... Non-LN Kidney Disease ... Nephritis #diagnosis #algorithm ... #sle #nephrology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... +GI+CVS+joints) ... • Amyloidosis (CVS ... to cold IgG • Lupus ... Paraproteinemias #Hematology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... involvement: Intractable nausea ... pain • Extra-CNS ... disorders (Systemic lupus ... Manifestations #diagnosis #neurology