13 results
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Kidney Injury (AKI ... • Hypercalcemia ... malignancies Treatment ... Kidney #Injury #AKI ... #Cancer #Oncology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... Urine Na+K / serum ... : Hypovolemia, Hypervolemia ... table #sodium #nephrology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
of breath • Neurologic ... Hyperphosphatemia • Hyperkalemia ... Hypocalcemia Hypercalcemia ... coma SIADH: • Hyponatremia ... differential #diagnosis #cancer
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- Urine Na/K/ ... Cl/urea/protein/ ... rhabdo/TLS) Causes ... #Nephrology #Diagnosis ... #Algorithm #Causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... , RTA Type IV, AI ... only if no clear cause ... Ca-gluconate or 1g CaCl ... #potassium #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... declines > ALT) • AKI ... Hyperuricemia • Hyponatremia ... + myoglobin AKI ... #treatment #nephrology
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
Management of Hyponatremia ... Cirrhosis - Correct K ... SIADH — look for cause ... #Management #algorithm ... #treatment #sodium
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... have fever - ACS ... , AKI, acute limb ... values: Elevated K, ... hydration - Hyperkalemia
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
2Cl- Symport (Loop ... • Hypercalcemia ... Kidney stones caused ... Tolvaptan) • Treatment ... and euvolemic hyponatremia
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential ... Diagnosis Algorithm ... in Cancer UOsm ... #algorithm #nephrology ... #oncology