12 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ... , others (RNP, aPL ... Anti-cardiolipin (aCl ... #diagnosis #associations ... #table
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid antibodies (aPL ... ): • Lupus anticoagulant ... Anticardiolipin antibodies (aCL ... of 1 clinical event ... #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... thiazidic, PPI, ACE ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Lupus is diagnosed using clinical and laboratory diagnostic criteria set by the American College of Rheumatology.
Lupus is diagnosed ... using clinical ... A diagnosis of lupus ... #SLE #Lupus #Erythematosus ... #Criteria #ACR
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... (for secondary APS ... Erythematosus #SLE ... #management #treatment
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... pericarditis • Hematologic ... Classification #Criteria #SLE ... Erythematosus #diagnosis
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... contact with cold air ... doi: 10.1111/all ... #rheumatology # ... comparison #table
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
dependent DM ACS ... event, follow ACC ... Change in clinical ... indication of AC ... • <12mo since ACS
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... rubella titer, ACE ... (to support a diagnosis ... ANA and RF (if clinical ... laboratory #workup #diagnosis
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
orthopnea, PND, LE ... • Avoid ARB/ACE-I ... Delivery • Stable ... defibrillator as ... GDMT meds (e.g., ACE