37 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #medications #druginduced
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... • Inhibit Na+ Cl ... #Pharmacology # ... nephrology #conversion
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
IL-2 therapy, Diuretics ... @kdjhaveri #DrugInduced ... #KidneyInjury #differential ... diagnosis #algorithm #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Hypertensive: • High Al ... >20 mEq/24 h - Diuretics ... #Hypokalemia #Differential ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Metabolic Alkalosis - Differential ... intake, Diuretics ... -: Diuretics, Bartter ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Metabolic Alkalosis - Differential ... intake, Diuretics ... -: Diuretics, Bartter ... Metabolic #Alkalosis #Differential ... Diagnosis #Algorithm #Nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... irrigation • Management ... Inhibitors of Na+K+2Cl ... Symport (Loop Diuretics ... #Nephrology #Pharmacology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Kidney loss of Cl ... loop or thiazide diuretics ... pressure: Active diuretic ... urine #Algorithm #nephrology ... #differential #
Ascites - Diagnosis and Management Summary
Paracentesis studies: cell count + differential, albumin, protein, culture
 • Serum-ascites-albumin-gradient
Diagnosis and Management ... : cell count + differential ... at start Diuretic ... avoid: NSAIDs, ACE ... Ascites #Diagnosis #Management
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
• Low Urine Cl ... - Loop diuretics ... , Thiazide diuretics ... urine #potassium #differential ... algorithm #diagnosis #nephrology