12 results
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
the Nephron #DrugInduced ... AcuteKidneyInjury #AKI #Nephrology ... #Pathophysiology ... #Pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... #medications #druginduced
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-Induced Edema ... Kat_Watson #DrugInduced ... #Causes #Differential ... #Pharmacology # ... Pathophysiology
Imaging Patterns of Toxic and Metabolic Brain Disorders

Thalami, Mammillary Bodies and Tectum: Wernicke Encephalopathy
Dentate Nuclei: Metronidazole,
Restricted Diffusion: ATL ... Parathyroid Disorders ATL ... Parieto-Occipital Vasogenic Edema ... Disorders #Clinical #Differential ... Diagnosis #Radiology #Neurology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Inhibitors of Na+K+2Cl ... Acute pulmonary edema ... • Edema associated ... Excretion #Diuresis #Nephrology ... #Pharmacology #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
matter vasogenic edema ... Etiology: • Pathophysiology ... circulation: MCA ACA ... Reversible course Differential ... diagnosis #management #neurology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... transfusion • HTN and edema ... • NSAIDs • ACE ... #hyperkalemia #differential ... potassium #high #nephrology
Numerous drugs taken by elderly persons can affect water balance by direct action on the kidney
#Diagnosis #Pharmacology ... #Geriatrics #Hyponatremia ... #Medications #DrugInduced ... #List #Differential
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... transfusion • HTN and edema ... • NSAIDs • ACE ... #hyperkalemia #differential ... potassium #high #nephrology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... myalgias, HoTN, edema ... initiation • Differential