62 results
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Thyrotoxicosis Medications ... Renal Losses ... Diagnosis #Algorithm #nephrology ... #low #potassium
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Injury (AKI) - Differential ... Compartment Syndrome, Medications ... Protein) • AIN: Medication ... Kidney #Injury #Differential ... #Diagnosis #nephrology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
algorithm Decreased renal ... potassium excretion ... • Acute renal ... Diagnosis #algorithm #nephrology ... #potassium #differential
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Exogenous (KCL ... #hyperkalemia #differential ... pathophysiology #pharmacology ... #potassium #medications
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair Renal ... Potassium Excretion ... Aldosterone Release: ACE ... Pathophysiology #Pharmacology ... #Renal
Causes of Hyperkalemia

Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
caused by excess potassium ... with impaired renal ... function, medication ... and underlying renal ... #Hyperkalemia #Differential
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Metolazone) 5) Potassium-sparing ... nephron #diuretics #pharmacology ... #nephrology #medications
Potassium Channel Blockers - Medications
1. Cardiovascular Drugs
2. Psychiatric drugs
3. Other drugs
4. Synthetic opioids: Levomethadyl 
5. Opium
Potassium Channel ... Blockers - Medications ... ChannelBlockers #Medications ... #Differential # ... Diagnosis #Pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... • NSAIDs • ACE ... • Recent IV potassium ... Medications 2. ... #high #nephrology
Management of Pediatric Kidney Stones
Acute Managment:
 • Pain relief: NSAIDs, opioids
 • Facilitating passage of stone:
Management of Pediatric ... Recurrence: • For ALL ... Monitoring for extra-renal ... Stones #Management #Pediatrics ... #nephrology #nephrolithiasis