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diagnosis management algorithm guidelines associations autoantibodies diseases granulomatosis polyangiitis table antibody antineutrophil antinuclear arteritis egpa eosinophilic erythematosus gpa lupus microscopic
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... antibodies) • ... Anti-cardiolipin (aCl ... Ill • ANCA Vasculitis ... ), C-ANCA (cytoplasmic
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... scleroderma) - Anti-Scl ... Vasculitis: • ... Jcortesizaguirr #ANA ... #diagnosis #rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (MPA) - ANCA ... Algorithm - ACR ... Polyangiitis #MPA #ANCA ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active
Polyangiitis (EGPA) - ANCA ... Algorithm - ACR ... #Polyangiitis #ANCA ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Disease Associations ANA ... Graves' disease c-ANCA ... granulomatosis p-ANCA ... diagnosis #table #rheumatology ... #antibodies
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
Management Algorithm - ACR ... MTX or AZA) with ... #Management #Treatment ... #ACR2021 #Guidelines ... #algorithm #rheumatology
Takayasu's Arteritis (TAK) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active TAK not on
Management Algorithm - ACR ... immunosuppressive Rx: MTX, AZA ... #Management #Treatment ... #ACR2021 #Guidelines ... #algorithm #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... erythematosus (ACLE ... Diagnosis: • ANCA-associated ... Serositis Labs: • ANA ... • (-) ANA + (+
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Males • Affects all ... Anti-Matrilin-1 Ab ○ Antibodies ... Nonspecific ↑ ESR, CRP, ANA ... affected tissue Treatment ... Polychondritis #rheumatology
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