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Nephron - Diuretic Sites of Action

Source Text: https://www.sciencedirect.com/book/9780323449427/critical-care-nephrology#book-info

#Nephron #Diuretics #Site #Action #Location #Nephrology #Pathophysiology #Pharmacology
Nephron - Diuretic ... Action Source Text ... book-info #Nephron #Diuretics ... #Pathophysiology ... #Pharmacology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... - Diuretic Sites ... Adenosine #Nephron #Pathophysiology ... #Action #nephrology ... #pharmacology
Mechanism of Action of Diuretics
Amiloride, Triamterene, Spironolactone
Loop Diuretics
Thiazides
Acetazolamide

#Diuretics #Mechanism #Action #pharmacology #pathophysiology #nephrology
Mechanism of Action of Diuretics ... Acetazolamide #Diuretics ... Mechanism #Action #pharmacology ... #pathophysiology ... #nephrology
Mechanisms of thiazide diuretic side effects

Dr. Muner Mohamed @MunerMohamed1

#thiazide #diuretic #pharmacology #pathophysiology #sideeffects #adverseeffects #nephrology
Mechanisms of thiazide diuretic ... #thiazide #diuretic ... #pharmacology # ... pathophysiology ... adverseeffects #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... • Inhibit Na+ Cl ... #Pharmacology # ... nephrology #conversion
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... irrigation • Management ... Inhibitors of Na+K+2Cl ... Symport (Loop Diuretics ... #Nephrology #Pharmacology
Central Nervous System Pharmacology - Somatic and Autonomic Receptors
Somatic
 • Rocuronium -> Non-depolarizing (reversible competitive inhibitors)
Nervous System Pharmacology ... the levels of Ach ... Parasympathetic “Rest ... Amy Chung, MD, MSc ... Autonomic #Receptors #Pharmacology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
activities • Diuretic ... release • ↓ Cl ... syndrome #Mechanisms #pathophysiology ... #nephrology
Outpatient Hypertension Management Algorithm
Monotherapy: 
 • Thiazide/thiazide-like 
 • ACE-I (non-black patients), 
 • ARB
Outpatient Hypertension Management ... Combined: • ACE-I ... or ARB + Diuretic ... Amy Chung, MD, MSc ... #Hypertension #Management
Acute Treatment of Migraine
Mild Attacks: NSAIDs, Simple Analgesics
Moderate/Severe Attacks: Triptans, Ditans, Gepants, Ergots
Non-pharmacologic Treatment: Neuromodulation, Rest,
Gepants, Ergots Non-pharmacologic ... Neuromodulation, Rest ... acute #treatment #management ... #neurology