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differential leukemia management classification cll lymphocytic aplastic blood criteria diffuse disorders hemeonc hemophagocytic lymphohistiocytosis lymphoma markers mcv mds myelodysplasia syndromes
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Age > 50 • Chronic ... #LAD #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Hepatomegaly, Lymphadenopathy ... Confusion Classic lab ... : ↑↑ ferritin, Anemia ... Thrombocytopenia, Neutropenia ... #hematology #criteria
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Thalassemia • Lead ... Hypothyroidism • Myelodysplasia ... #Algorithm #Causes ... #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Presentation: • Lymphadenopathy ... • Dyspnea • Fever ... Weight loss • Anemia ... classification #hematology ... #oncology #management
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
ALL) - PAS, TdT Lymphadenopathy ... T-cell - CD7, CD3 Chronic ... Disorders - Myelodysplastic ... Pelger-Huet, Macrocytic anemia ... Blood #Disorders #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Fevers > 100.5 ... Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... ) B symptoms → fevers ... PRCA, autoimmune neutropenia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myeloproliferative Disease • Neutropenia ... compounds, alcohol, lead ... #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Difficulty breathing • Neutropenia ... and petechiae Causes ... • Hypocellular myelodysplastic ... #oncology #hematology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... or functional neutropenia ... • HSM • Fevers ... #Leukemia #Hematology ... #Oncology #Diagnosis
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