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hematology algorithm antibiotics febrile hemophagocytic lp lymphohistiocytosis pediatrics stepbystep stratification syndrome abscess apml causes cayetanensis chronic classification cll cyclospora cyclosporiasis
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... There are clear ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Summary myelo ( ... and risk-stratification ... • Risks: infection ... #Management #treatment ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
frequently affects infants ... following: • Fever ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... • Clinical: fever ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... #EBM #Management ... #Pediatrics #Peds ... Stratification #Fever
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) - Summary ... ) B symptoms → fevers ... chemotherapy for low-risk ... Lymphocytic #Leukemia #oncology ... #diagnosis #management
Cyclosporiasis - Diagnosis and Management Summary Pathogen: • Cyclospora cayetanensis • Foodborne, waterbone, and soil-transmitted. •
and Management ... Summary Pathogen ... Risk Factors: ... diarrhea, Low-grade fever ... #management #treatment
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Summary Lung ... pneumonia • DM risk ... : • 80% have fever ... Intervention: - Fevers ... #treatment #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Attempt if high risk ... Subacute-Acute: • Common: fever ... #management #hematology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Risk ... • Dyspnea • Fever ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... #oncology #management
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