41 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... inherited bleeding disorder ... bruising • Skin ... factor VIII) Treatment ... #Diagnosis #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... • Rheumatic disorders ... • Celiac disease ... effect following treatment ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... thrombocythemia), Autoimmune disease ... vonWillebrand #Syndrome #Diagnosis ... #Management #treatment ... #hematology #differential
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... - Differential Diagnosis ... of hair, eyes, skin ... • Addison's disease ... #skin #dermatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... Differential Diaqnoses ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... glucocorticoid treatment ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Advanced Liver Disease ... Malignancy, Autoimmune disorders ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cryoglobulinemia Associated Disorders ... thrombophlebitis, pulmonary ... Cryofibrinogenemia Diagnosis ... Cryofibrinogenemia #diagnosis ... hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... and lower jaw Treatment ... disease. ... #Dermatology