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differential management antinuclear lupus antibody classification erythematosus leukemia systemic testing antibodies arthritis autoimmune chronic cll cytoplasmic disorders druginduced lymphocytic myositis
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
: - SLE, SSc ... : - SjS, SLE, ... Speckled: - SLE ... #differential #diagnosis ... #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... erythematosus (SLE ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... : The ANA patterns ... Patterns and Associated ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
: • SLE, SSc, ... : • SjS, SLE, DM ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... /full triad at diagnosis ... Can also see mechanics ... Autoimmune #Myositis #diagnosis ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... constitutional symptoms ... Workup: - ANA ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
involvement 3% SLE-Related ... Auto-Antibodies: - ANA ... Lupusreference #SLE ... autoantibodies #signs #symptoms ... #differential #rheumatology
Arthritis of the Hand - Arthritis Patterns Osteoarthritis: • Osteoarthritis of the hand usually involves the DIP and
Hand - Arthritis Patterns ... ulnar deviation • SLE ... Joint Involvement Patterns ... #hand #diagnosis ... #rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... pylori test (GI symptoms ... function test, ANA ... (e.g., SLE), anti-phospholipid ... Causes #Workup #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... • Is there a pattern ... constitutional symptoms ... asymmetric pattern ... #MSK #rheumatology
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