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diagnosis hematology causes algorithm oncology workup management aplastic hemolysis hemolytic leukemia thrombocytopenia thrombocytosis agglutinin b12 cancer chronic cll cold deficiency
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
with Pancytopenia ... - Differential ... malignancies • Infection ... Toxins • Aplastic Anemia ... #Neutropenia #Differential
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
: • Recurrent infections ... from neutropenia ... Diagnosis: • Pancytopenia ... antibiotics if neutropenic ... management #treatment #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... deficiency Infections ... Diagnosis #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... Difficulty breathing • Neutropenia ... - recurrent infections ... Idiopathic • Infections ... #oncology #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential ... HLH syndrome 5. ... Acquired Aplastic Anemia ... marrow failure syndrome ... #Workup #Differential
Approach to the Rash in a an oncology patient - MINT-C Mnemonic M - Malignancy: Leukemia cutis,
, Viral infections ... Dermatoses: Sweet Syndrome ... ie petechiae), Neutropenia-specific ... Rash #oncology #differential ... MINTC #Mnemonic #dermatology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
and Differential ... HLH syndrome 5 ... Acquired Aplastic Anemia ... marrow failure syndrome ... #Workup #Differential
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... , Kostmann syndrome ... Chediak-Higashi syndrome ... Megaloblastic anemia-rare ... #differential #
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... Hemolytic uremic syndrome ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
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