38 results
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... syndrome (ST-HUS ... anemia" • HELLP syndrome ... #schistocytes #differential ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... ) - HELLP syndrome ... uremic syndrome ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemoptysis - Differential Diagnosis Framework
Airways: 
 • Bronchitis
 • Bronchiectasis
 • Malignancy: Primary bronchogenic CA, Endobronchial
Hemoptysis - Differential ... , Idiopathic pulmonary ... Osler-Weber-Rendu syndrome ... #Differential # ... Diagnosis #pulmonary
Causes of Hemoptysis - Differential Diagnosis Algorithm
Massive Hemoptysis (>I00 mL in 24 hours)
 • Malignancy
 •
Causes of Hemoptysis ... - Differential ... Algorithm Massive Hemoptysis ... Goodpasture's Syndrome ... #Differential #
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
thrombocytopenic purpura/hemolytic ... uremic syndrome ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... Wiskott-Aldrich syndrome ... Antibody-mediated hemolysis ... #Pancytopenia #Differential ... #Diagnosis #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... Urobilinogen #Hemolysis ... #Differential # ... Diagnosis #hematology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Syndrome Definition ... Fever, Hematuria, Hemoptysis ... symptomatology Differential ... #differential #
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Deficiency Anemia - Differential ... extravascular) hemolysis ... athletic training, Pulmonary ... Gastrectomy, WHDA syndrome ... Algorithm #ferritin #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... blood loss, Acute hemolysis ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... Thrombocytosis #Platelets #Differential