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hematology differential eosinophils hes hypereosinophilia lysis tumor algorithm anemia aplastic apml differentiation hypereosinophilic leukemia leukostasis mds monoclonal myelodysplastic paraproteinemias treatment
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
disorders • Diagnosis ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... and Management ... #diagnosis #hematology ... #differential #management
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
of Tumor Lysis Syndrome ... Laboratory TLS ... #TumorLysis #Syndrome ... #TLS #diagnosis ... #management #oncology
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... MatthewHoMD #TLS ... #diagnosis #management ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... Myelodysplastic #Syndrome ... #Management #treatment ... #hematology #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... leukapheresis - TLS ... #TLS #diagnosis ... #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... - Hepatitis, eosinophilic ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
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