10 results
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Drug-Induced Thrombocytopenia ... purpura. ... #Diagnosis #Hematology ... #Thrombocytopenia ... #Medications #Causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... inflammation • Thrombocytopenia ... : - Thrombocytopenia ... • Secondary Causes ... Differential #Diagnosis #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... of Pregnancy (AFLP ... child * Severe cases ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... child * Severe cases ... @Bloodman #Thrombocytopenia ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... Extravascular #Causes ... differential #diagnosis #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
considered in all cases ... Heparin-induced thrombocytopenia ... coagulation and other causes ... of purpura fulminans ... pathophysiology #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... decrease in most cases ... hematuria (without casts ... Diagnosis #Workup #Hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Post Transfusion Purpura ... Causes purpura & ... severe thrombocytopenia ... TRALI): Leading cause ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Post Transfusion Purpura ... Causes purpura & ... severe thrombocytopenia ... TRALI): Leading cause ... more likely to cause