26 results
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Pathogenesis and Clinical ... excess secretion of hCG ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Pathogenesis and Clinical ... the etiology Signs ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Cirrhosis - Diagnosis Algorithm ... Symptoms: Fatigue ... quadrant discomfort Signs ... Associated history: Symptoms ... Diagnose PBC if 2/3 criteria
Diagnostic Algorithm for Suspected Pulmonary Embolism

Well's Criteria for PE
 • Clinical Signs and Symptoms of DVT
Diagnostic Algorithm ... Embolism Well's Criteria ... for PE • Clinical ... Signs and Symptoms ... AcutePE #Diagnosis #Algorithm
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... tissue expansion (e.g ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... share the same pathophysiology ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
/SYMPTOMS: • CENTRAL ... Signs and symptoms ... McDonald diagnostic criteria ... patients with clinically ... stimulation Clinical
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Pathogenesis and Clinical ... Findings Symptoms ... included in DSM 5 criteria ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... fibers Spectrum of Clinical ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... fasciculations Common Symptoms ... diagnosis: months - Criteria ... : El Escorial criteria ... EMG: LMN Signs in