8 results
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Alcoholic Hepatitis (AH ... ischemic hepatitis (e.g ... use assessment (e.g ... laboratory tests (e.g ... #hepatology #criteria
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... autoimmune disease (e.g ... Diagnose PBC if 2/3 criteria ... specific ANAs (e.g ... Diagnosis #Algorithm #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
of information (e.g ... non-essential drug/HDS treatments ... Benign/malignant biliary ... vascular disorder (e.g ... Diagnosis #Algorithm #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
inflammation (eg ... been reported (eg ... of Hepatitis (eg ... Histology Findings (eg ... Diagnosis #Management #Hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
underlying disease (eg ... • Infection (eg ... Histopathologic criteria ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Primary Biliary Cirrhosis - Management
A. Initiate therapy 
 - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... UDCA (13-15 mg/kg ... /or prognostic criteria ... Cirrhosis #Management #Treatment ... #hepatology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Diagnosis (Clinical Criteria ... IV albumin (1 g/kg ... Treatment Overview ... liver insult (e.g ... Hepatorenal #Syndrome #Hepatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g ... Diagnosis #Management #Hematology