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diagnosis differential autoantibodies dermatology oncology acute ana antibodies antinuclear autoimmune behcet clinical comparison connectivetissuediseases ctild dermatosis diseases erythematosus febrile gammopathy
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
late-onset nemaline myopathy ... capillary leak syndrome ... • Schnitzler syndrome ... Ig deposition disease ... Differential #Diagnosis #hematology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Associations ANA ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Autoantibodies #Associations ... #table #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... PSS: Sjogren syndrome ... Differential #Comparison #Table ... #Pulmonary #Rheumatology ... #Associations
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
that occurs in association ... connective tissue disease ... antisynthetase syndrome ... IIMs #diagnosis #rheumatology ... #dermatology #Myopathy
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
for Sweet Syndrome ... Association with ... inflammatory disease ... neutrophils #Sweet #Syndrome ... #Diagnosis #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... • Heavy Chain disease ... late-onset nemaline myopathy ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
with disease activity ... SLE-SSc-AlM overlap syndromes ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology ... #table #ANA
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... Asia • HLA-B51 association ... tests in Behcet syndrome ... : monoclonal TNF-aIpha ... signs #symptoms #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... Antisynthetase syndrome ... (also seen in association ... • If myopathy ... #rheumatology #
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