9 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Associations ANA ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Autoantibodies #Associations ... #table #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... PSS: Sjogren syndrome ... Differential #Comparison #Table ... #Pulmonary #Rheumatology ... #Associations
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
that occurs in association ... connective tissue disease ... antisynthetase syndrome ... IIMs #diagnosis #rheumatology ... #dermatology #Myopathy
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
for Sweet Syndrome ... Association with ... inflammatory disease ... neutrophils #Sweet #Syndrome ... #Diagnosis #Hematology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
with disease activity ... SLE-SSc-AlM overlap syndromes ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology ... #table #ANA
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... Asia • HLA-B51 association ... tests in Behcet syndrome ... diagnosis #management #signs ... #symptoms #rheumatology
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Rheumatoid Arthritis - Signs ... neuropathy, Cervical myelopathy ... Thrombocytosis, Felty's syndrome ... Arthritis #RA #Signs ... Symptoms #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... (also seen in association ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Autoimmune diseases ... Presentation • Common Signs ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... Diagnosis #Management #Hematology