20 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Cerebral Salt Wasting ... Neurological event 2) Sodium ... Pathophysiology #diagnosis ... #nephrology #hyponatremia ... #comparison
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential Diagnosis ... Osmolarity 3) Urine Sodium ... Uric Acid → renal salt ... #Algorithm #nephrology ... #sodium #low #uricacid
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
syndrome - Na-K-2Cl ... cell epithelial sodium ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Comparison of Causes of Salt-Wasting in Infancy
 - PHA 1
 - PHA 3
 - 21-OH CAH
Comparison of Causes ... of Salt-Wasting ... Wasting #Infancy #Comparison ... #differential #diagnosis ... #pediatrics #nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
- Differential Diagnosis ... insipidus Excessive salt ... #Differential #Diagnosis ... #Causes #nephrology ... #sodium #high
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
osmostat, Cerebral salt ... Hyponatremia #Algorithm #diagnosis ... #sodium #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
losses, Cerebral salt ... Hyponatremia #algorithm #diagnosis ... #sodium #low #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... Hypervolemic (Excess salt ... #Differential #Diagnosis ... Workup #Algorithm #nephrology ... #sodium
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
autosomal recessive salt-losing ... thiazide-sensitive sodium-chloride ... Pathophysiology #nephrology ... #diagnosis
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
: SIADH, Renal Sodium ... Insufficiency, Cerebral Salt ... #differential #diagnosis ... #table #sodium ... #nephrology