74 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
limb Gitelman syndrome ... cell epithelial sodium ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Effects of Strokes by Location - Anterior vs Posterior Localization

Anterior Circulation 
 - MCA 
 -
Circulation - MCA ... Artery #Strokes #Syndromes ... Territory #Symptoms #Signs ... #Diagnosis #Table ... Review in Clinical Neurology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential Diagnosis ... Osmolarity 3) Urine Sodium ... Uric Acid → renal salt ... #Algorithm #nephrology ... #sodium #low #uricacid
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... hypertrophy • Sodium ... release • ↓ Cl ... #cardiorenal #syndrome ... pathophysiology #nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Cirrhosis, Nephrotic syndrome ... osmostat, Cerebral salt ... Hyponatremia #Algorithm #diagnosis ... #sodium #nephrology
Guillain-Barre Syndrome
An acute polyneuropathy (disorder Of the peripheral nervous System).
Symptoms are Often symmetrical and progress Over
Guillain-Barre Syndrome ... GuillainBarre #Syndrome ... #Diagnosis #Neurology ... #Signs
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... autosomal recessive salt-losing ... thiazide-sensitive sodium-chloride ... Pathophysiology #nephrology ... #diagnosis
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... Hypervolemic (Excess salt ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
- Differential Diagnosis ... insipidus Excessive salt ... #Differential #Diagnosis ... #Causes #nephrology ... #sodium #high
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
losses, Cerebral salt ... Cirrhosis, Nephrotic syndrome ... Hyponatremia #algorithm #diagnosis ... #sodium #low #nephrology