29 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... : - Neuro: AMS ... Lysis Syndrome: • Pathophysiology ... #diagnosis #management ... #hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
and initial management ... based primarily on clinical ... tests, which are also ... #Diagnosis #Management ... #Hematology #HIT
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... (for secondary APS ... CNS #neurology #rheumatology ... #management #treatment
THROMBOELASTOGRAPHY (TEG)
General Principle
• A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
breakdown, and also ... formation begins as ... Thromboelastography #Diagnosis ... #Management #CriticalCare ... #Hematology #Interpretation
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
, causes and management ... cryoglobulinemia vasculitis Clinical ... anti-infectious therapy as ... Cryoglobulinemia #Vasculitis #Rheumatology ... #Management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... : • Clinical Suspicion ... D/c all heparin ... non-heparin A/C if clinical ... #Hematology #HemeOnc
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... Findings: • ↑AST/ALT ... ) Differential Diagnosis ... Maternal Support - Critical ... #management #pathophysiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... opacities • Diagnosis ... unless severe APLS ... coagulopathy, RRT/IMV as ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... #management #treatment ... #summary #rheumatology