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diagnosis management hematology neurology differential antiphospholipid erythematosus oncology sle systemic algorithm aps guidelines barre classification comparison cppd dermatology disease druginduced
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... (for secondary APS ... CNS #neurology #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... : • Pathophysiology ... Low calcium • Treatment ... #management #hematology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... severe disease Treatment ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
BEE Syndromes - ... is important, as ... diagnosis and treatment ... • Sjögren syndrome ... • Systemic lupus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as ... disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Farr assay) and lupus ... Can also be measured ... Associated with SLE-SSc-AlM ... overlap syndromes ... erythematosus #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Epidemiology: -10% of all ... constitutional symptoms • Treatment ... life-threatening • Treatment ... comparison #table #rheumatology
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... (APS) APS is a ... antibodies (aPL): • Lupus ... to be present Treatment ... Antiphospholipid #Syndrome
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... Differentiation #Syndrome
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS Venous Thrombosis - Arterial Thrombosis INR Target Duration Recurrence Dr. Laurent ARNAUD
Antiphospholipid Syndrome ... Antiphospholipid #Syndrome ... #APS #management ... EULAR2019 #guidelines #rheumatology ... #hematology #treatment
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