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differential causes nephrology high hypomagnesemia hypomg binders binding classification comparison diuresis diuretics druginduced drugs excretion hypernatremia k low magnesium management
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... Agents to Treat Hyperkalemia ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... MunerMohamed1 #hyperkalemia ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Etiologies of Hypernatremia - Differential Diagnosis GI losses / Insensible losses Sodium Overload Transcellular Movement of Water Central Diabetes Insipidus
- Differential Diagnosis ... Water Central Diabetes ... in kidneys) - Medications ... - Chronic hypokalemia ... #Table #Causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... • Recent IV potassium ... (Uncontrolled diabetes ... Medications 2. ... #causes #potassium
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Renal Loses - Medications ... - Hypokalemia ... - Uncontrolled diabetes ... #Differential #Diagnosis ... Low #Magnesium #Table
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... • Recent IV potassium ... (Uncontrolled diabetes ... Medications 2. ... #causes #potassium
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... Elimination (see Table ... STOP offending medications ... #Treatment #potassium
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
Correction of diabetic ... osmotic diuresis - Potassium ... Hypomagnesemia #Causes #diagnosis ... #differential #medications ... #drugs #pharmacology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome • Diagnosis ... Hyponatremia • Hypercalcemia ... • Nephrogenic diabetes ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
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