10 results
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... An acute, life-threatening ... (both ALL and AML ... #Syndrome #TLS ... #oncology #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Pathophysiology ... #APML #diagnosis ... management #hematology #oncology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... - Summary Acute ... Pathophysiology ... Diagnosis: • ... #treatment #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: • Pathophysiology ... : - Neuro: AMS ... , AKI, acute limb ... Syndrome: • Pathophysiology ... #diagnosis #management
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... malignancies Treatment ... Interleukin-2) • Tumor lysis ... #AKI #Cancer #Oncology ... #Differential #Diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Overview: ALL, CML, AML ... , APML, CLL Acute ... Score • CML -> AML ... Lymphadenopathy AML ... #Diagnosis
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... TLS (tumor-lysis ... : - Seen with AML ... (~20 %) and APL ... #HemeOnc #Diagnosis
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... the underlying pathophysiology ... and cauda equina TREATMENT ... #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... edema visualized as ... , ADEM, Acute toxic ... #neurology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... hepatitis, or acute ... Pathophysiology: ... Treatment Overview ... be substituted as