9 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
child * Severe cases ... #HELLP #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Imaging options for exclusion of PE in pregnant women
The radiation dose required for either V/Q scanning
are outlined in Table ... 1 #Diagnosis ... #Obstetrics #OBGyn ... Workup #Imaging #Comparison ... #Table #Pregnant
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Fatty Liver of Pregnancy ... child * Severe cases ... #HELLP #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... , ↑Tbili/Dbili/AP ... #hepatology #obstetrics ... #obgyn #diagnosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in Pregnancy ... Cholestasis of Pregnancy ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential #diagnosis
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... shock, Obstetric ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
- Differential Diagnosis ... Intravenous Drug Use • Pregnancy ... Hyperhomocysteinemia - Heparin-induced ... coagulation and other causes ... Venous #Arterial #pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... transfusion • Pathophysiology ... #diagnosis #comparison ... #table
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... cholestasis of pregnancy ... malignancies, Hepatic ... #workup #hepatology