26 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Evaluate an Abnormal APTT ... Step 1: Is the PT ... or APTT Artifactually ... Heparin, or Direct Thrombin ... Prolonging the PT
Coagulation cascade and anticoagulants 

Satyendra Dhar MD, @DharSaty

#coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
xarelto #DOAC #vWF #thrombin ... #ptt #pt
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... typically prolong PT ... drugs e.g. direct thrombin ... #Abnormal #PT
Multiple LV Thrombi on Echocardiogram
Too much of a bad thing

- Ivan Stankovic, MD, PhD

#Multiple #LV #Thrombi
Multiple LV Thrombi ... #Multiple #LV ... #Thrombi #thrombus ... clinical #cardiology #a4c
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Coagulation Tests PT ... / INR, aPTT, Anti-Xa ... Clotting Time, Thrombin
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Thrombus in transit ... Pt had extensive ... later with normal LV ... Echocardiogram #A4C ... PulmonaryEmbolism #Thrombus
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... drugs (e.g. direct thrombin ... #Abnormal #PT
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
• Elevation in thrombin ... platelet aggregation PT ... , aPTT: • Expected ... can accelerate thrombin ... using INR use PT
LV Thrombus on Echocardiogram

Omid Kiamanesh, MD @OKiamanesh

#LV #Thrombus #Echocardiogram #clinical #cardiology #a4c
LV Thrombus on Echocardiogram ... @OKiamanesh #LV ... #Thrombus #Echocardiogram ... clinical #cardiology #a4c
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
12-13 g/dL, • ANC ... iron studies, PT ... /aPTT Differential